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Daniel J Lodge, Ph.D.

Professor & Chair

Currently seeking M.S. & Ph.D. students

In a broad sense, my laboratory is interested in better understanding the mechanisms underlying psychiatric disease with the goal of developing novel therapeutics. To do this we utilize a number of approaches including optogenetics, in vivo electrophysiology, behavioral and molecular methods. Using such an approach, we have identified what we believe to be a key pathology in schizophrenia, specifically a loss of interneuron function in the ventral hippocampus. This has led to a hypothesis that restoring interneuron function may be a novel therapeutic approach for schizophrenia. We are currently investigating the utility of stem cell derived interneuron transplants in rodent models of schizophrenia and autism.