Faculty Directory

David Kadosh, Ph.D.

Professor

Department of Microbiology, Immunology & Molecular Genetics

Currently seeking M.S. & Ph.D. students

Microbiology, Molecular Biology and Molecular Genetics

Fungal Pathogenesis   Regulation of morphology, virulence and virulence-related properties in Candida species   Our research is focused is on molecular mechanisms that control fungal pathogenesis with an emphasis on Candida species, the 4th leading cause of hospital-acquired bloodstream infections in the U.S. A wide variety of immunocompromised individuals, including cancer patients, organ transplant recipients and AIDS patients, are susceptible to infection. We are particularly interested in transcriptional and translational mechanisms that control Candida albicans virulence and several key virulence-related properties, including morphogenesis, biofilm formation and antifungal resistance, in response to host environmental cues. We also carry out studies to determine how and why certain Candida species have evolved to become more pathogenic than others.   Related Diseases: Cancer, heart disease, AIDS, most immunosuppressive diseases   Techniques: Molecular biology, microbiology, molecular genetics, genomics, bioinformatics, cell biology, biochemistry   Visit Dr. David Kadosh's lab »